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The role of chemotherapeutics in anti-tunor treatment.
| Chemotherapeutics | Cancer types | Pyroptosis signaling | References |
|---|---|---|---|
| Paclitaxel | Lung cancer | Caspase-3/GSDME | 108 |
| α-NETA | Ovarian cancer | Caspase-4/GSDMD | 132 |
| Doxorubicin | Melanoma | eEF-2K/GSDME | 123 |
| Lobaplatin | cervical cancer | Caspase-3/GSDME | 109 |
| 5-FU | Gastric cancer | Caspase-3/GSDME | 86 |
| Cisplatin | ESCC | Caspase-3/GSDME | 133 |
| Carboplatin | Retinoblastoma | Caspase-3/GSDME | 134 |
| DHA | ESCC | PKM2-caspase-8/3-GSDME | 122 |
