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. Author manuscript; available in PMC: 2023 Sep 12.
Published in final edited form as: Nat Biotechnol. 2023 Apr;41(4):447–449. doi: 10.1038/s41587-023-01690-2

Fig. 1 |. MZmine, an open-source community project for integrative LC-IMS-MS and IMS-MS data processing.

Fig. 1 |

a, Overview of active developments and key additions to MZmine since the first publication, which led to over 180 modules that now drive interactive, reproducible, and efficient data processing and visualization in MZmine 3. b, Data exchange formats and direct interfaces enable downstream analysis with strong ties to projects like GNPS, SIRIUS, and MetaboAnalyst. c, The integrative LC- and IMS-MS imaging workflow applies feature detection in RT, ion mobility, and m/z dimension to MS data stored in open or vendor formats. Comprehensive processing and annotation results are merged into d, an aligned feature list with one ion feature detected in LC-IMS-MS samples and aligned to one MALDI-IMS-MS ion feature image. Annotation results (Lipid annotation column) and interactive charts include the table columns Shapes (extracted ion chromatograms), Mobilograms (extracted ion mobilograms), and Images (extracted ion images).