Table 1.
Baseline data and clinical characteristics by baseline FPG quartiles in non-diabetic patients with ACI
| Variables | Overall n=1496 | Baseline FPG quartiles | P value | |||
| Q1 (n=369) |
Q2 (n=377) |
Q3 (n=372) |
Q4 (n=378) |
|||
| Age (years) | 64.0 (55.0,74.0) | 65.0 (54.0,74.0) | 65.0 (56.0,75.0) | 63.5 (55.0,73.0) | 65.0 (56.0,75.0) | 0.266 |
| Sex, n (%) | 0.026 | |||||
| Male | 956 (63.9) | 260 (70.5) | 233 (61.8) | 232 (62.4) | 231 (61.1) | |
| Female | 540 (36.1) | 109 (29.5) | 144 (38.2) | 140 (37.6) | 147 (38.9) | |
| Medical insurance type, n (%) | 0.259 | |||||
| Urban employees’ medical insurance | 663 (44.3) | 148 (40.1) | 164 (43.5) | 177 (47.6) | 174 (46) | |
| New type rural cooperative medical system | 637 (42.6) | 175 (47.4) | 168 (44.6) | 146 (39.2) | 148 (39.2) | |
| Commercial insurance | 4 (0.3) | 2 (0.5) | 1 (0.3) | 0 (0) | 1 (0.3) | |
| Out-of-pocket medical | 192 (12.8) | 44 (11.9) | 44 (11.7) | 49 (13.2) | 55 (14.6) | |
| Education level, n (%) | 0.737 | |||||
| Elementary or below | 736 (49.2) | 193 (52.3) | 190 (50.4) | 178 (47.8) | 175 (46.3) | |
| Middle school | 286 (19.1) | 69 (18.7) | 69 (18.3) | 74 (19.9) | 74 (19.6) | |
| High school or above | 474 (31.7) | 107 (29) | 118 (31.3) | 120 (32.3) | 129 (34.1) | |
| Smoking, n (%) | 0.539 | |||||
| Never smoking | 814 (54.4) | 186 (50.4) | 203 (53.8) | 208 (55.9) | 217 (57.4) | |
| Smoking cessation | 299 (20.0) | 83 (22.5) | 76 (20.2) | 67 (18) | 73 (19.3) | |
| Current smoking | 383 (25.6) | 100 (27.1) | 98 (26) | 97 (26.1) | 88 (23.3) | |
| Alcohol consumption, n (%) | 379 (25.3) | 100 (27.1) | 78 (20.7) | 109 (29.3) | 92 (24.3) | 0.042 |
| Prior stroke, n (%) | 395 (26.4) | 87 (23.6) | 91 (24.1) | 109 (29.3) | 108 (28.6) | 0.169 |
| Hypertension, n (%) | 1013 (67.7) | 241 (65.3) | 249 (66). | 254 (68.3) | 269 (71.2) | 0.312 |
| Atrial fibrillation, n (%) | 107 (7.2) | 21 (5.7) | 28 (7.4) | 21 (5.6) | 37 (9.8) | 0.091 |
| Admission NIHSS Score, (IQR) | 4.0 (2.0, 6.0) | 3.0 (2.0, 6.0) | 3.0 (2.0, 5.0) | 4.0 (2.0, 5.0) | 4.0 (2.0, 7.0) | < 0.001 |
| Pneumonia, n (%) | 0.134 | |||||
| No | 1428 (95.5) | 354 (95.9) | 365 (96.8) | 356 (95.7) | 353 (93.4) | |
| Yes | 68 (4.5) | 15 (4.1) | 12 (3.2) | 16 (4.3) | 25 (6.6) | |
| BMI (kg/m2) | 23.6±3.1 | 23.1±3.0 | 23.4±3.1 | 23.7±3.0 | 24.2±3.1 | < 0.001 |
| SBP on admission (mm Hg) | 145.0±21.6 | 143.7±21.5 | 145.5±21.5 | 145.7±21.6 | 145.3±21.9 | 0.579 |
| DBP on admission (mm Hg) | 85.8±12.6 | 85.9±13.0 | 86.3±12.5 | 86.0±12.3 | 85.1±12.5 | 0.639 |
| Heart rate (beats/min) | 74.4±10.2 | 73.2±9.5 | 74.3±10.6 | 74.6±10.0 | 75.7±10.5 | 0.01 |
| Total cholesterol (mmol/L) | 4.3±1.0 | 4.2±1.0 | 4.2±0.9 | 4.4±1.0 | 4.5±1.2 | < 0.001 |
| Triglycerides (mmol/L) | 1.6±1.4 | 1.5±1.0 | 1.5±1.0 | 1.6±1.3 | 1.8±2.0 | 0.002 |
| HDL cholesterol (mmol/L) | 1.1±0.3 | 1.1±0.3 | 1.1±0.3 | 1.1±0.3 | 1.2±0.3 | 0.855 |
| LDL cholesterol (mmol/L) | 2.6±0.8 | 2.4±0.8 | 2.5±0.7 | 2.6±0.8 | 2.7±0.9 | < 0.001 |
| FPG (mmol/L) | 5.2±1.0 | 4.2±0.3 | 4.7±0.1 | 5.2±0.2 | 6.5±1.1 | < 0.001 |
| Alanine aminotransferase (U/L) | 19.0 (14.0, 28.0) | 17.9 (13.0, 26.0) | 18.0 (13.0, 25.0) | 20.0 (14.0, 29.0) | 21.0 (15.0, 31.6) | < 0.001 |
| Aspartate aminotransferase (U/L) | 22.0 (18.0, 28.0) | 21.0 (17.0, 26.6) | 21.0 (17.0, 26.0) | 22.0 (18.0, 29.0) | 23.0 (18.1, 31.2) | < 0.001 |
| Alkaline phosphatase (U/L) | 79.3±36.3 | 76.7±26.3 | 78.2±26.4 | 82.3±51.9 | 80.1±34.2 | 0.191 |
| Serum creatinine (µmol/L) | 74.6±28.6 | 75.4±24.4 | 74.8±35.5 | 74.0±29.1 | 74.1±24.0 | 0.91 |
| Blood urea nitrogen (mmol/L) | 5.1±1.9 | 5.1±2.1 | 5.0±1.6 | 5.0±2.0 | 5.1±1.9 | 0.886 |
| Uric acid (µmol/L) | 291.4±96.8 | 294.6±89.4 | 293.3±96.2 | 288.2±95.6 | 289.6±105.5 | 0.791 |
| Leucocyte count (×109 /L) | 6.8±2.5 | 6.5±2.1 | 6.4±1.9 | 6.8±2.7 | 7.6±2.8 | < 0.001 |
| 1 year mortality, n (%) | 102 (6.8) | 18 (4.9) | 21 (5.6) | 20 (5.4) | 43 (11.4) | < 0.001 |
ACI, acute cerebral infarction; BMI, body mass index; DBP, diastolic blood pressure; FPG, fasting plasma glucose; HDL, high-density lipoprotein; LDL, low-density lipoprotein; NIHSS, National Institutes of Health Stroke Scale; SBP, systolic blood pressure.