Table 2.
Multivariable Cox regression analysis of the association between baseline FPG and all-cause mortality in non-diabetic patients with ACI
| Outcomes | N | Events, N (%) |
Unadjusted | Adjusted | ||
| HR (95% CI) |
P value | HR (95% CI) |
P value | |||
| All-cause mortality at 3 months | ||||||
| Baseline FPG (every increase of 1 mmol/L) | 1546 | 50 (3.2) | 1.35 (1.13 to 1.62) | 0.001 | 1.27 (1.02 to 1.58) | 0.03 |
| Q1 (<4.52) | 377 | 8 (2.1) | Reference | Reference | ||
| Q2 (4.52–4.98) | 385 | 8 (2.1) | 0.98 (0.37 to 2.6) | 0.963 | 0.94 (0.33 to 2.66) | 0.911 |
| Q3 (4.99–5.55) | 385 | 13 (3.4) | 1.63 (0.68 to 3.93) | 0.278 | 2.15 (0.84 to 5.52) | 0.111 |
| Q4 (>5.55) | 399 | 21 (5.3) | 2.61 (1.16 to 5.89) | 0.021 | 2.43 (0.98 to 6.04) | 0.056 |
| P for trend | 0.006 | 0.012 | ||||
| All-cause mortality at 12 months | ||||||
| Baseline FPG (every increase of 1 mmol/L) | 1496 | 102 (6.8) | 1.32 (1.16 to 1.50) | <0.001 | 1.17 (1.02 to 1.35) | 0.03 |
| Q1 (<4.52) | 369 | 18 (4.9) | Reference | Reference | ||
| Q2 (4.52–4.98) | 377 | 21 (5.6) | 1.14 (0.61 to 2.14) | 0.684 | 1.04 (0.53 to 2.03) | 0.913 |
| Q3 (4.99–5.55) | 372 | 20 (5.4) | 1.11 (0.59 to 2.1) | 0.745 | 1.37 (0.7 to 2.68) | 0.36 |
| Q4 (>5.55) | 378 | 43 (11.4) | 2.42 (1.39 to 4.19) | 0.002 | 2.08 (1.13 to 3.82) | 0.019 |
| P for trend | 0.001 | 0.005 | ||||
Adjusted variables included age, sex, smoking, alcohol consumption, NIHSS Score at admission, pneumonia, prior stroke, hypertension, atrial fibrillation, alkaline phosphatase, serum creatinine and body mass index;.
ACI, acute cerebral infarction; FPG, fasting plasma glucose; NIHSS, National Institutes of Health Stroke Scale.