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(A) Schematic illustration of cell membrane-targeting self-delivery nanodrugs for high-efficient and anti-metastatic combinational LTPTT/PDT (low-temperature photothermal therapy/photodynamic therapy). (B) CLSM images of 4T1 cells treated with CP (Cypate-RRKK-PEG8-COOH) and CCP (2 μM) for 30 min. (C) CLSM images of the cell membrane disruption of CCP (2 μM) pretreated 4T1 cells under high power intensity of NIR laser. Reproduced with permission from [69] . Copyright 2022 Elsevier Ltd.
