Fig. 4.

(A) Schematic illustration of localized CPT and anti–PD-1 delivery using an in situ formed supramolecular hydrogel to attain bioresponsive drug release and TME regulation. (B) Experimental schedule. (C) Representative flow cytometric analysis of CD3⁺ T and (D) CD8⁺ T cell infiltration within the tumor by different treatment groups. Reproduced with permission from [98]. Copyright 2020 The Authors, some rights reserved; Exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).