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Schematic illustration of the photothermal genome-editing strategy for cancer immunotherapy. (A) Process of preparation of ANP/HSP-Cas9 plasmid complex. (B) Illustration of photothermal activation for PD-L1 genome editing in tumor cells. (C) Photoactivable CRISPR-Cas9 strategy reprograms immunosuppressive tumor environment. Reproduced with permission from [105]. Copyright 2021 Wiley-VCH GmbH.
