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Pharmacokinetics Parameters of Free NOB and NOB/SD in Healthy SD Rats (n = 3)
| Formulations | Tmax (h) | Cmax (μg/mL) | AUC0–12 (µg· h/mL) | Fr (%) |
|---|---|---|---|---|
| Free NOB | 0.83±0.14 | 1.26±0.51 | 2.89±1.28 | 100 |
| NOB/SD | 0.67±0.14 | 7.23±1.62* | 9.68±1.74* | 325±135 |
Note: *P<0.05.
