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. 2023 Aug 21;5(1):vdad102. doi: 10.1093/noajnl/vdad102

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Published by Oxford University Press on behalf of the Society for Neuro-Oncology and the European Association of Neuro-Oncology 2023. This work is written by (a) US Government employee(s) and is in the public domain in the US.

This work is written by (a) US Government employee(s) and is in the public domain in the US.

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Figure 1. — PTEN-deficient glioblastoma cells are highly sensitive to LMP400. (A) PTEN protein expression in a panel of patient-derived GBM cells and GSC cells by Western blot. (B) The LMP400 IC₅₀ in each cell line was examined at 72 hours post-treatment. (C) Comparison of LMP400 IC₅₀ values between PTEN-expressing and PTEN-deficient cells.