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. 2023 Aug 21;5(1):vdad102. doi: 10.1093/noajnl/vdad102

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Published by Oxford University Press on behalf of the Society for Neuro-Oncology and the European Association of Neuro-Oncology 2023. This work is written by (a) US Government employee(s) and is in the public domain in the US.

This work is written by (a) US Government employee(s) and is in the public domain in the US.

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Figure 6. — LMP400 and Niraparib offer improved bioavailability than current analogs. (A) Comparison of survival of HEK293 cells stably expressing common ATP-Binding Cassette (ABC) transporters upon treatment with LMP400, Topotecan, or SN-38. (B) Comparison of survival of HEK293 cells stably expressing common ABC transporters upon treatment with Niraparib or Olaparib.