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The effect of curcumin on orofacial allodynia induced by pT-ION. (A) The primary mechanical hyperalgesia in area V2. (B) The secondary mechanical hyperalgesia in area V3. (C) The secondary cold allodynia in area V3. N = 8 mice/group. *P < 0.05 and ***P < 0.001 vs. sham group; ###P < 0.001 vs. pT-ION group, one-way ANOVA and Tukey’s test.
