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. 2023 Aug 25;15(16):8458–8470. doi: 10.18632/aging.204984

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Copyright: © 2023 Zhi et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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The role of curcumin on the decrease of dendritic spine density induced by pT-ION in the mice hippocampal CA1 region. (A) The representative Golgi-Cox-staining images showing the density and morphology of dendritic spines in the cone cell layer of hippocampal CA1 region in each group (scale bar: 5 μm). (B) The analysis of total dendritic spine density in each group. (C) The analysis of mushroom-type dendritic spine density in each group. N = 8 mice/group. ^*P < 0.05 and ^***P < 0.001 vs. sham group; ^###P < 0.001 vs. pT-ION group, one-way ANOVA and Tukey’s test.