Figure 1.
Ion channels and transporters showing the flow of cations and anions in T cells. Abbreviations. CFTR—cystic fibrosis transmembrane conductance regulator, CRAC—Ca2+ release-activated channel, GABA—γ-amino butyric acid, P2X—purinergic receptor, T—T cell, TRP—transient receptor potential family, leucine-rich repeat-containing 8 protein (LRRC8) receptors eg LRRCBA. N-methyl-D- aspartate (NMDA); Magnesium transporter protein 1 (MAGT1); Voltage-gated proton channels (Hvcn1); TRP mulcolipin (TRPM), ZIP 6, zinc transporter.