Table 1.

Functional effects of store-operated Ca2⁺ entry (SOCE) on T cells.

Controls T cell proliferation (2, 7, 14, 15)

T cell migration (40, 41)

Apoptosis (42)

Cytokine production (43–45)

Transcriptional regulation (43–45)

Controls the development and function of T cells (2, 7, 14) /T regs (10, 46, 47)

Controls proliferation, and expansion of CD4+/CD8+ cells (9)

Regulates function of TH17 cells (10, 47, 48)

Controls germinal center reaction and humoral immunity (49, 50)

Tregs development in the thymus (43, 51)