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. 2023 Sep 12;83(9):1138–1147. doi: 10.1055/a-2150-9440

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The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.

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Fig. 1 — Twenty-five genomic alterations with potential therapeutical consequences (Level of evidence I-II according to ESMO/ESCAT) detected in 18 metastatic breast cancer patients by next generation sequencing based whole exome sequencing. Five patients had two and one patient three different alterations (CNG = copy number gain, mut = mutation).