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. 2023 Aug 7;30(9):1380–1392. doi: 10.1038/s41594-023-01047-y

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 6 — a-c, Coordination of (a) Mg1 (green) and (b) Mg2 by tetracycline (blue) and waters (red balls) and phosphate-oxygens of 16S rRNA determined here, compared with (c) previous structures PDB ID 1I97²⁷, 1HNW²⁶, 4V9A⁹³, 5J5B⁹⁴ and 5J7L⁹⁴. Distances are provided for the green dashed lines. d-f, Coordination of (d) Mg1 (green) and (e) Mg2 by eravacycline (blue) and waters (red spheres) and phosphate-oxygens of 16S rRNA determined here, compared with (f) previous structures of eravacycline (PDB ID 7M4W)³¹ and tigecycline (PDB ID 4V9B⁹³, 4YHH¹⁰⁰, 5J91⁹⁴ and 6YTF¹⁰¹). Distances are provided for the green dashed lines.