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. 2023 Aug 29;14:1237260. doi: 10.3389/fendo.2023.1237260

Table 3.

Metabolic parameters and serum ion after acupuncture and sham acupuncture.

Acupuncture group Sham acupuncture group
Pre-treatment
(n = 458)		 Post-treatment
(n = 458)		 p p Pre-treatment
(n = 468)		 Post-treatment
(n = 468)		 p a p p1 a p1
Biological features
Weight (kg) 62.53 ± 12.39 62.26 ± 12.39 0.7382 0.7895 63.78 ± 12.45 63.52 ± 11.98 0.7410 0.7683 0.9118 0.9011
BMI (kg/m2) 23.99 ± 4.29 23.90 ± 4.29 0.7424 0.7915 24.47 ± 4.23 24.39 ± 4.10 0.7488 0.7782 0.8839 0.8954
Waist (cm) 85.10 ± 11.61 84.85 ± 11.54 0.7391 0.7677 85.75 ± 11.35 85.39 ± 11.09 0.6134 0.6378 0.9752 0.9761
Hip (cm) 98.25 ± 8.49 98.15 ± 8.58 0.8607 0.8814 98.65 ± 8.76 98.45 ± 8.58 0.7115 0.7279 0.8975 0.8912
WHR 161.24 ± 5.02 161.24 ± 5.08 0.9887 0.7548 0.87 ± 0.07 0.87 ± 0.07 0.7101 0.7328 0.8666 0.8638
Systolic pressure (mmHg) 112.00 ± 9.33 112.07 ± 8.59 0.9024 0.8631 112.61 ± 9.49 112.48 ± 8.51 0.8248 0.8321 0.486 0.4861
Diastolic pressure (mmHg) 74.80 ± 7.86 74.95 ± 7.54 0.7725 0.7577 74.91 ± 7.93 75.48 ± 7.73 0.2598 0.2525 0.3863 0.3822
Respiration (beats/min) 18.09 ± 1.69 17.96 ± 1.72 0.2204 0.2308 18.01 ± 1.51 18.02 ± 1.76 0.8988 0.9181 0.109 0.1162
Pulse (beats/min) 75.91 ± 6.33 76.03 ± 6.39 0.7769 0.7647 76.22 ± 6.15 76.20 ± 5.94 0.9668 0.9624 0.8016 0.8114
Ferriman-Gallwey 3.14 ± 2.85 2.81 ± 2.70 0.0639 0.0670 2.93 ± 2.76 2.67 ± 2.66 0.1420 0.1465 0.5203 0.5105
Acne score 0.70 ± 0.46 0.24 ± 0.43 <0.0001 <0.0001 0.65 ± 0.48 0.27 ± 0.44 <0.0001 <0.0001 0.0096 0.0102
Acanthosis nigricans 1.21 ± 0.47 0.18 ± 0.44 <0.0001 <0.0001 1.21 ± 0.48 0.19 ± 0.44 <0.0001 <0.0001 0.81 0.8395
Metabolic parameters
HOMA-IR 23.82 ± 28.76 26.24 ± 33.12 0.2381 0.2310 21.68 ± 21.29 23.28 ± 22.70 0.2706 0.2659 0.8554 0.8736
Metabolic syndrome 71(14.2) 57(11.4) 0.1851 0.1831 83(16.6) 68(13.6) 0.1852 0.1840 - -
FPG (mmol/L) 5.07 ± 0.93 5.07 ± 1.27 0.9712 0.9980 5.01 ± 1.04 4.99 ± 1.19 0.7457 0.6999 0.5941 0.5654
FINS (pmol/L) 99.18 ± 96.88 107.25 ± 105.13 0.2243 0.2199 92.97 ± 78.74 100.59 ± 86.67 0.1609 0.1565 0.8581 0.8393
Hcy (μmol/L) 8.39 ± 5.07 6.76 ± 4.29 <0.0001 <0.0001 8.29 ± 4.64 6.26 ± 3.69 <0.0001 <0.0001 0.1128 0.0972
HDL-C (mmol/L) 1.29 ± 0.36 1.33 ± 0.41 0.1140 0.1175 1.26 ± 0.38 1.29 ± 0.39 0.2772 0.2872 0.6753 0.6600
LDL-C (mmol/L) 3.00 ± 0.89 2.86 ± 1.06 0.0346 0.0365 2.93 ± 0.86 2.75 ± 0.91 0.0012 0.0012 0.6249 0.5895
Lipoprotein α(mg/L) 132.65 ± 101.58 187.75 ± 111.97 <0.0001 <0.0001 126.32 ± 97.97 176.7 ± 113.90 <0.0001 <0.0001 0.4808 0.5429
Total cholesterol (mmol/L) 4.80 ± 1.10 4.65 ± 1.28 0.0610 0.0691 4.68 ± 1.07 4.51 ± 1.16 0.0213 0.0204 0.9273 0.8891
Triglyceride (mmol/L) 1.59 ± 0.95 1.49 ± 0.85 0.0969 0.1055 1.55 ± 0.87 1.56 ± 0.98 0.8853 0.8612 0.046 0.0476
Apolipoprotein A1(g/L) 1.53 ± 0.31 1.57 ± 0.38 0.0382 0.0403 1.49 ± 0.32 1.54 ± 0.36 0.0202 0.0223 0.63 0.6351
Apolipoprotein B (g/L) 0.91 ± 0.29 0.88 ± 0.33 0.2024 0.2166 0.89 ± 0.28 0.86 ± 0.29 0.1231 0.1269 0.8685 0.8823
ApoA1/ApoB 1.84 ± 0.70 1.99 ± 0.77 0.0023 0.0024 1.80 ± 0.59 1.94 ± 0.66 0.0007 0.0008 - -
Serum ion test
Ca (mmol/L) 1.95 ± 0.43 2.04 ± 0.55 0.0026 0.0025 1.96 ± 0.39 2.02 ± 0.55 0.0703 0.0608 0.2101 0.1942
P (mmol/L) 1.13 ± 0.26 1.11 ± 0.30 0.4308 0.4418 1.15 ± 0.34 1.13 ± 0.38 0.5444 0.6009 0.8068 0.7768
Mg (mmol/L) 0.86 ± 0.18 0.88 ± 0.21 0.2758 0.2735 0.87 ± 0.15 0.87 ± 0.21 0.7689 0.7219 0.3738 0.3536
K (mmol/L) 4.14 ± 0.92 4.44 ± 1.97 0.0032 0.0032 4.23 ± 0.88 4.32 ± 1.73 0.3369 0.3435 0.0516 0.0502
Na (mmol/L) 135.66 ± 16.12 136.96 ± 22.03 0.3085 0.3129 136.53 ± 14.21 136.61 ± 22.21 0.9485 0.9258 0.233 0.2180
Cl (mmol/L) 93.39 ± 12.24 97.88 ± 17.92 <0.0001 <0.0001 94.08 ± 10.86 97.60 ± 18.04 0.0003 0.0003 0.2471 0.2324

Data are median (IQR).

p-values represent comparison before and after treatment within acupuncture and sham acupuncture groups.

a

p-values represent comparison before and after treatment within acupuncture and sham acupuncture groups after adjusting clomiphene and reproductive outcome.

p1-values represent comparison of the difference value before and after treatment between acupuncture and sham acupuncture groups.

a

p1-values represent comparison of the difference value before and after treatment between acupuncture and sham acupuncture groups after adjusting clomiphene and reproductive outcome.