Table 4.
The outcomes of a Cox regression analysis of OS-related factors impacting NSCLC patients treated with ICIs.
| variable | One-way analysis of variance | Multifactorial analysis | ||
|---|---|---|---|---|
| HR (95%CI) | P | HR (95%CI) | P | |
| Age>60 | 1.352 (1.206-1.459) | 0.340 | – | – |
| Male | 1.570 (1.299-1.826) | 0.216 | – | – |
| Smoking | 1.601 (1.523-1.739) | 0.382 | – | – |
| Combined BLI | 0.612(0.508-0.719) | 0.597 | 0.739 (0.651-0.843) | 0.816 |
| PS Rating | ||||
| 0~1 | 1 | – | – | – |
| 2~3 | 1.429 (1.306-1.518) | 0.659 | – | – |
| Squamous cancer | 0.832 (0.770-0.893) | 0.516 | – | – |
| PD-L1 expression | ||||
| Negatives | 1 | – | – | – |
| 1%~49% | 1.318(1.119-1.534) | 0.338 | – | – |
| ≥50% | 1.329(1.227-1.410) | 0.826 | – | – |
| Treatment programme | ||||
| Immunological monotherapy | 1 | – | – | – |
| Combination chemotherapy | 0.829 (0.726-0.891) | 0.401 | – | – |
| Combination radiotherapy | 1.419(1.352-1.510) | 0.329 | – | – |
| Combined anti-angiogenic therapy | 1.262 (1.198-1.306) | 0.135 | – | – |
| Number of immunotherapy lines | ||||
| ≥2 | 1 | – | 1 | – |
| 1 | 0.525 (0.446-0.627 | <0.001 | 0.526 (0.448-0.619) | <0.001 |