Table 3.

Patient-reported physical burden of ATTR-CM by NYHA class.

	All patients N = 208	Patients who were NYHA class I/II n = 156	Patients who were NYHA class III n = 43
Unable to walk normally, n (%)	127 (61.7%) [n = 206]	86 (55.8%) [n = 154]	36 (83.7%) [n = 43]
Unable to participate in social or leisure activities in the past 3 months, n (%)	59 (28.9) [n = 204]	36 (23.7) [n = 152]	23 (53.5) [n = 43]
Median days (IQR)	25.0 (10.0, 85.0) [n = 49]	11.0 (5.0, 80.0) [n = 30]	80.0 (43.0, 90.0) [n = 19]
Unable to do household chores in the past 3 months, n (%)	55 (27.1) [n = 203]	31 (20.5) [n = 151]	22 (51.2) [n = 43]
Median days (IQR)	48.0 (10.0, 90.0) [n = 46]	20.0 (10.0, 90.0) [n = 27]	62.0 (30.0, 92.0) [n = 19]
Family member had to do your household chores because of your ATTR-CM in the past 3 months, n (%)	63 (31.0) [n = 203]	34 (22.4) [n = 152]	26 (61.9) [n = 42]
Median days (IQR)	62.0 (10.0, 90.0) [n = 51]	66.0 (10.0, 90.0) [n = 28]	62.0 (10.0, 92.0) [n = 23]
Hours of chores, median (IQR)	3.0 (2.0, 6.0) [n = 52]	3.0 (2.0, 5.0) [n = 30]	4.5 (2.0, 12.0) [n = 22]

ATTR-CM, transthyretin amyloid cardiomyopathy; IQR, interquartile range; NYHA, New York Heart Association.