Table 3.
Gut hormones: gastrin family: their mode of delivery, site of action, their physiologic effects, and the levels post-RPC surgery and cited references
| Hormone | Modes of delivery | Site of action | Effects | Levels in RPC | Cited references |
|---|---|---|---|---|---|
|
| |||||
| Gastrin | Endocrine | Stomach (parietal cells) | ↑ Gastric acid secretion | Identical | Inoue et al. 1982, Greenberg et al. 1989, M’Koma et al. 1999 |
| Ghrelin | Endocrine | Stomach (A-like cells) | ↑ Gastric emptying | No study in RPC | – |
| Paracrine | ↑ Gastric motility | ↑ in modulating immune response inflammatory colitis | Chang et al. 2003, Brzozowski et al. 2004, Dixit et al. 2004, Korbonits et al. 2004, Granado et al. 2205 | ||
| Cholecystokinin | Endocrine | Gall bladder | ↑ Contraction of gallbladder | ↑ in RPC | Salemans et al. 1995, Hallgren et al.1995, van Battum et al. 1999 |
| Small intestine | ↓ Gastric emptying | ||||
| ↑ Pancreatic enzyme secretion | |||||
| ↑ Memory enhancement Satiation | |||||
RPC Restorative proctocolectomy, IPAA ileal pouch anal anastomosis