TABLE 6.

Target values of lipid-lowering targets.

Risk level	LDL-C recommended target values (mmol/L)	Recommended classification	Evidence level
Low risk	<3.4 (Cholesterol Treatment Trialists Collaborators, 2012)	Ⅱa	B
Medium and high riska	<2.6 (Ridker et al., 2008; Cholesterol Treatment Trialists Collaboration, 2010; Cholesterol Treatment Trialists Collaboration, 2015; Yusuf et al., 2016a)	I	A
Very high risk	<1.8 and >50% reduction from baseline (Cholesterol Treatment Trialists Collaboration, 2010; Cannon et al., 2015; Bangalore et al., 2016; Ridker et al., 2016; Sabatine et al., 2017; Schwartz et al., 2018)	I	A
Ultra-high risk	<1.4 and >50% reduction from baseline (Cholesterol Treatment Trialists Collaboration, 2010; Cannon et al., 2015; Bangalore et al., 2016; Ridker et al., 2016; Sabatine et al., 2017; Schwartz et al., 2018)	I	A

LDL-C: low-density lipoprotein cholesterol.^a See the section on diabetes in special populations for lipid targets in ASCVD, high-risk patients with comorbid diabetes. Non-HDL-C, target level = LDL-C + 0.8 mmol/L.