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. 2023 Aug 15;13(9):5958–5973. doi: 10.21037/qims-23-126

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2023 Quantitative Imaging in Medicine and Surgery. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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X-Tile software was used to determine correlations between macrophage expression and survival time. The image color represents the correlation intensity of each partition from low (dark/black) to high (bright green/red). Green represents a direct correlation, and red represents a reverse correlation between expression level and characteristic survival rate. (A) The best cutoff value of CD68+ TAMs was 14.80%. The relationship between high and low CD68+ TAM expression and survival time is shown (P=0.002). (B) The best cutoff value of CD163+ TAMs was 18.30%. The relationship between high and low CD163+ TAM expression and survival time is shown (P=0.001). TAMs, tumor-associated macrophages.