Table 1. Correlation between Gb CD68+ macrophage infiltration and clinical and MRI features.
| Characteristic | Total (N=140) | CD68 (%) | r | P |
|---|---|---|---|---|
| Gender | 0.718 | 0.474 | ||
| Male | 82 (58.57) | 6.84 (2.83, 14.72) | ||
| Female | 58 (41.43) | 9.32 (4.42, 14.22) | ||
| Age (year) | 52.84±11.44 | 7.39 (3.21, 14.33) | 0.230 | 0.006* |
| Ki-67 (%) | 40.00 (30.00, 50.00) | 7.39 (3.21, 14.33) | −0.137 | 0.106 |
| Lateralization of tumor | 0.136 | 0.873 | ||
| Left | 68 (48.57) | 7.17 (2.95, 14.55) | ||
| Right | 59 (42.14) | 8.85 (4.35, 14.38) | ||
| Bilateral | 13 (9.29) | 6.73 (3.93, 12.54) | ||
| Major location of the tumor | 2.559 | 0.041* | ||
| Frontal lobe | 46 (32.86) | 6.46 (2.42, 12.85) | ||
| Temporal lobe | 61 (43.57) | 9.46 (5.68, 17.17) | ||
| Parietal lobe | 10 (7.14) | 4.86 (2.70, 9.21) | ||
| Occipital lobe | 15 (10.71) | 6.54 (3.69, 14.17) | ||
| Other | 8 (5.71) | 4.42 (2.13, 9.26) | ||
| Necrosis/cystic | 0.122 | 0.903 | ||
| Yes | 125 (89.29) | 7.39 (3.41, 17.26) | ||
| No | 15 (10.71) | 11.30 (2.70, 17.26) | ||
| Hemorrhage | −1.502 | 0.135 | ||
| Yes | 38 (27.14) | 10.20 (4.46, 16.35) | ||
| No | 102 (72.86) | 6.78 (3.08, 13.87) | ||
| Degree of enhancement | 4.228 | 0.017* | ||
| None | 8 (5.71) | 2.06 (0.55, 6.46) | ||
| Mild/minimal | 24 (17.14) | 4.72 (1.08, 10.53) | ||
| Marked/avid | 108 (77.14) | 9.25 (4.66, 14.97) | ||
| ADCmean (SD) (×10−6 mm2/s) | 886.63±107.60 | 7.39 (3.21, 14.33) | 0.070 | 0.414 |
| ADCmin (SD) (×10−6 mm2/s) | 788.09±116.62 | 7.39 (3.21, 14.33) | 0.081 | 0.344 |
Data are shown as n (%) or mean ± SD or median (Q1, Q3). *, P<0.05, P values are statistically significant. Gb, glioblastoma; MRI, magnetic resonance imaging; ADC, apparent diffusion coefficient; SD, standard deviation.