Table 3. Macrophage infiltration associations with molecular features of Gb.
| Characteristic | Total (N=140) | CD68 (%) | CD163 (%) | |||||
|---|---|---|---|---|---|---|---|---|
| Value | r | P | Value | r | P | |||
| P53 | −2.209 | 0.029* | −1.263 | 0.209 | ||||
| Positive | 84 (60.00) | 9.44 (4.69, 14.74) | 15.73±9.01 | |||||
| Negative | 56 (40.00) | 5.82 (1.67, 11.92) | 13.85±7.99 | |||||
| MGMT methylation | −0.974 | 0.332 | −1.260 | 0.210 | ||||
| Positive | 70 (50.00) | 10.03 (3.17, 14.63) | 15.90±8.61 | |||||
| Negative | 70 (50.00) | 7.04 (3.21, 13.14) | 14.06±8.62 | |||||
| TERT | −2.969 | 0.004* | −2.201 | 0.031* | ||||
| Mutant | 90 (64.29) | 10.89 (4.70, 14.71) | 15.75 (10.62, 22.47) | |||||
| Wild | 50 (35.71) | 5.21 (1.42, 9.39) | 11.24 (4.38, 20.99) | |||||
Data are shown as n (%) or mean ± SD or median (Q1, Q3). *, P<0.05, P values are statistically significant. Gb, glioblastoma; MGMT, O6-methyl-guanine DNA methyl-transferase; TERT, telomerase reverse transcriptase.