Table 2. Risk of Incident Dementia According to Sedentary Behavior Quartiles.
| Sedentary behavior by quartile of mean daily time | ||||
|---|---|---|---|---|
| Quartile 1 (1.96-<8.08 h/d) | Quartile 2 (8.08-<9.27 h/d) | Quartile 3 (9.27-<10.44 h/d) | Quartile 4 (≥10.44 h/d) | |
| Incident dementia | ||||
| No. of cases | 82 | 82 | 96 | 154 |
| Person-years | 83 670 | 83 775 | 83 874 | 83 617 |
| Cases per 1000 person-years | 0.98 | 0.98 | 1.14 | 1.84 |
| Minimally adjusted modela | ||||
| HR (95% CI) | 1.11 (0.82-1.51) | 1 [Reference] | 1.14 (0.85-1.53) | 1.73 (1.32-2.27) |
| P value | .50 | .38 | <.001 | |
| Fully adjusted modelb | ||||
| HR (95% CI) | 1.14 (0.84-1.55) | 1 [Reference] | 1.09 (0.81-1.47) | 1.50 (1.14-1.99) |
| P value | .41 | .57 | .004 | |
Abbreviation: HR, hazard ratio.
a
Adjusted for age and sex.
b
Adjusted for age, sex, education, Townsend Deprivation Index, presence of APOE ε4 allele, ethnicity, chronic conditions (heart or vascular disease, diabetes, or cancer), self-reported health, smoking status, alcohol consumption, diet, body mass index, self-reported depression, and time spent engaged in moderate to vigorous physical activity.