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Incidence of hepatic tumours in male and female F344 rats exposed to Ozokerite for two consecutive years (Kuroda et al., 2013)
| Males | Females | |||||
|---|---|---|---|---|---|---|
| Doses | 0 | 0.1% | 0.2% | 0 | 0.1% | 0.2% |
| Number of animals | 50 | 50 | 50 | 50 | 50 | 50 |
| Hepatocellular adenoma | 0 | 6 (a) | 5 (a) | 0 | 3 | 2 |
| Cholangiocarcinoma | 0 | 1 | 0 | 0 | 0 | 0 |
| Cholangiosarcoma | 0 | 0 | 1 | 0 | 0 | 0 |
| Total | 0 | 7 (a) | 6 (a) | 0 | 3 | 2 |
Statistically different from control (p < 0.05).
