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NLRP3 and IL-1β are over-expressed in IBD patients (n = 6). Representative images of NLRP3 immunostaining in distal colon of normal individuals and IBD patients. Scale bar: 100 μm (A). Quantification of NLRP3 (B). Representative images of IL-1β immunostaining in the colon of normal individuals and IBD patients. Scale bar: 100 μm (C). Quantification of IL-1β (D). ##p < 0.01 compared with normal individuals.
