FIGURE 4.

Clinical photographs of Patients 2, 4, and 5. (A–G) Patient 2 at age 65 years, showing jaw protrusion (A), hands with thick fingers and wrinkled palms (B), hypermobile finger joints (C,D), hyperextensible skin (E), atrophic scars at surgical sutures (F), and valgus/flat feet (G). (H–J) Patient 4 at age 27 years, showing finger joint hypermobility (H,I) and skin hyperextensiblity (J). (K–N) Patient 5 at age 47 years, showing marked finger joint hypermobility (K,L) and skin hyperextensibility (M) and redundancy (N).