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. 2023 Aug 30;11:1236331. doi: 10.3389/fpubh.2023.1236331

Table 1.

Information for exposures and outcomes.

Phenotype Unit Sample size Ancestry Consortium/cohort Author Year of publication/release PubMed ID
Job involves heavy manual or physical work Categorical ordered 263,615 European MRC-IEU Ben Elsworth 2018
Job involves mainly walking or standing Categorical ordered 263,556 European MRC-IEU Ben Elsworth 2018
Work/job satisfaction Categorical ordered 105,358 European MRC-IEU Ben Elsworth 2018
Lifetime smoking index SD 462,690 European UK Biobank Wootton et al. 2019 31689377
BMI SD 806,834 European GIANT + UK Biobank Pulit et al. 2018
WHR SD 697,734 European GIANT + UK Biobank Pulit et al. 2018
WHR adjusted for BMI SD 694,649 European GIANT + UK Biobank Pulit et al. 2018
Major depression Binary 500,199 (170,756 cases) European PGC + UK Biobank Howard et al. 2019 30718901
Mood swings Binary 451,619 (204,412 cases) European MRC-IEU Ben Elsworth 2018
Sleep time SD 91,105 European UK Biobank Doherty et al. 2018 30531941
Sedentary behavior SD 91,105 European UK Biobank Doherty et al. 2018 30531941
Overall physical activity SD 91,105 European UK Biobank Doherty et al. 2018 30531941
Education attainment SD 766,345 European SSGAC + UK Biobank Lee et al. 2018 30038396
Low back pain Binary 273,994 (25,163 cases) European FinnGen Kurki et al. 2022

BMI, Body Mass Index; WHR, Waist-to-Hip Ratio; MRC-IEU, The MRC Integrative Epidemiology Unit; GIANT, Genetic Investigation of ANthropometric Traits Consortium; PGC, Psychiatric Genomics Consortium; SSGAC, Social Science Genetic Association Consortium.