Table 2.

The results for sensitivity analysis.

Exposures	Heterogeneity test		Pleiotropy test				MR-PRESSO distortion test	MR-Steiger directionality test
	Cochran’s Q statistic	p	MR-Egger regression		MR-PRESSO global test		p
			Intercepts	p	p (before removing outliers)	p (after removing outliers)
Job involves heavy manual or physical work	66.99	<0.001	0.029	0.204	<0.001	0.100	0.702	Correct causal direction
Job involves mainly walking or standing	23.41	0.037	−1.12e-05	0.999	0.052	–	–	Correct causal direction
Work/job satisfaction	54.97	<0.001	−0.004	0.771	<0.001	0.017	0.831	Correct causal direction