Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Sep 13;42:239. doi: 10.1186/s13046-023-02813-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 2 — Effects of Circ-RAPGEF5 on the proliferation and invasion in vitro. A-B CCK8 assays to test cell growth viability of Circ-RAPGEF5 knockdown or overexpression in RBE and CCLP1 cells. C-D EdU labelling assays to test the cell proliferation ability. E–F Colony formation assays to evaluate cell long-term proliferation ability. G-H Cell cycle analysis detected by flow cytometry in Circ-RAPGEF5 knockdown or overexpression cells. I-J The invasion ability was assessed by Matrigel substrated transwell assay in Circ-RAPGEF5 knockdown or overexpression cells. All data are presented as the means ± SD of three independent experiments. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001