Table 3.
Statistically significant DE cfRNAs in CSF of “heterogeneous” SMA patients at T6 compared to T0, and of “homogeneous” SMA patients at T6 compared to T0
| mRNA | lncRNA | Other biotype | |
|---|---|---|---|
| “Heterogeneous” T6 vs T0 | |||
| Up-regulated | 13 | 0 | 1 |
| Down-regulated | 1 | 0 | 0 |
| Subtotal | 14 | 0 | 1 |
| Total | 15 | ||
| “Homogeneous” T6 vs T0 | |||
| Up-regulated | 7 | 0 | 1 |
| Down-regulated | 1 | 0 | 0 |
| Subtotal | 8 | 0 | 1 |
| Total | 9 | ||
mRNAs, lncRNAs and “other biotype” (processed pseudogenes, unprocessed pseudogene and untranscribed unprocessed pseudogenes) number is represented in terms of up-regulated transcripts, down-regulated transcripts, subtotal and total. Transcripts were considered as DE when |log2(T6/T0)| was ≥ 0.5 and a FDR was ≤ 0.1