Skip to main content
. 2023 Aug 30;10:1236136. doi: 10.3389/fvets.2023.1236136

Figure 5.

Figure 5

(A) Xenograft tumor section presenting a neoplasia, classified as high grade centroblastic diffuse malignant lymphoma. The neoplasia consists of monomorphic large cells with a high cell density and a starry-sky pattern. Hematoxylin and eosin (H&E) stained. Magnification = 100× , scale bar = 100 μm. (B) Xenograft tumor section presenting a lymphoma. The neoplastic is composed by monomorphic round cells, with several marginal and small nucleoli per cell and high mitotic index. Hematoxylin and eosin (H&E) stained. Magnification = 400×, scale bar = 20 μm. (C) Xenograft tumor section presenting the immunohistochemistry technique for B-cells, exhibiting positive staining on the cellular membrane level in virtually 100% of the tumor. Anti-CD20 antibody, Gill's hematoxylin. Magnification = 400×, scale bar = 20 μm. (D) Xenograft tumor section presenting the immunohistochemistry technique for T-cells, showing that the tumor cells are negative for this marker (anti-CD3, Gill's hematoxylin, 100x). Anti-CD3 antibody, Gill's hematoxylin. Magnification = 400×, scale bar = 20 μm.