Table 3.

Features selected by RENT with at least 25% frequency for predicting DFS.

Input group	Feature	Frequency (%)
Clinical factors D1	HPV-related	98
	TNM8 stage	89
	Smoking (pack year)	41
	Tumor site—oral cavity	39
	Tumor site—oropharynx	37
Radiomics features D2	Shape feature—tumor sphericity	95
	PET texture—LBP_102	95
	Shape feature—tumor Elongation	69
	CT texture—GLSZM small area low gray level emphasis	63
	PET texture—LBP_201	48
	PET texture—GLSZM gray level non uniformity normalized	31
All tabular data. Clinical factors D1 + radiomics features D2	Shape feature—tumor sphericity	98
	Shape feature—tumor elongation	95
	PET texture—LBP_102	94
	CT texture—GLSZM small area low gray level emphasis	85
	PET texture—LBP_201	68
	HPV related	55
	PET texture—GLSZM gray level non uniformity normalized	49
	TNM8 stage	47