Table 4.

Features selected by RENT with at least 25% frequency for predicting OS.

Input group	Feature	Frequency (%)
Clinical factors D1	TNM8 stage	100
	HPV-related	95
	Smoking (pack year)	47
	Tumor site—oropharynx	36
Radiomics features D2	Shape feature—tumor sphericity	100
	CT texture—GLCM joint average	79
	CT texture—GLCM sum average	79
	Shape feature—major axis length	57
	CT first order—maximum discrete HU	35
	PET texture—GLRLM high gray level run emphasis	34
	Shape feature—maximum tumor 3D diameter	31
	PET texture—GLCM cluster shade	25
All tabular data. Clinical factors D1 + radiomics feature D2	Shape feature—tumor sphericity	100
	TNM8 stage	88
	HPV-related	86