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. 2023 Aug 30;14:1229636. doi: 10.3389/fimmu.2023.1229636

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Copyright © 2023 Li, Li, Liu, He, Dong, Dong and Zhang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Odds ratio for association of genetically predicted systemic inflammatory regulators with chronic kidney disease. CTACK, cutaneous T-cell attracting; GROa, growth regulated oncogene alpha; SDF-1a, stromal-cell-derived factor 1 alpha; NGF-B, beta-nerve growth factor; SCGF-B, stem cell growth factor beta; IL, interleukin; TNF-β, tumor necrosis factor beta; TRAIL, TNF-related apoptosis inducing ligand; MR, mendelian randomization; CI, confidence internal; OR, odds ratio; IVW-FE, inverse-variance weighted fixed-effects MR; IVW-RE, inverse-variance weighted random-effects MR; WM, weighted median; IVR, instrumental variable ratio (Wald) estimator; SNP, single nucleotide polymorphism. P value for heterogeneity based on Cochran's Q statistic for IVW, and Rücker's Q for MR-Egger.