Table 2. Presence of select annotations per genome.

Function	Gene	HI01-Me	HI03-Me	HI04-Me	HI02-NTM	HI03-NTM	HI04-NTM	Citation
Metabolism
Ammonium import	amt	✓			✓	✓	✓	[18]
	amtB	✓	✓	✓				[18]
Caffeine breakdown	cdhA		✓	✓	✓			[19]
	cdhB		✓		✓			[19]
	cdhC		✓	✓	✓			[19]
Nicotinic acid breakdown	nicA	✓	✓	✓				[20]
	nicB	✓	✓	✓				[20]
Metal Homeostasis
Iron transport	irtA				✓	✓	✓	[21]
	iscA	✓	✓	✓				[22]
Magnesium transport	corA	✓	✓	✓	✓	✓	✓	[23, 24]
	mgtA	✓	✓	✓	✓	✓	✓	[25]
Divalent cation transport	mntH	✓	✓	✓	✓	✓	✓	[26, 27]
Toxic Metal Tolerance
Arsenic resistance	acr3	✓	✓		✓		✓	[28]
	arsB	✓	✓	✓	✓	✓	✓	[29]
	arsC	✓	✓	✓	✓	✓	✓	[30]
Cadmium transport	cadA	✓						[31]
Copper tolerance	copA	✓	✓	✓	✓	✓		[32–34]
	mctB				✓	✓	✓	[35]
Heavy metal tolerance	atm1	✓	✓	✓				[36]
Lithium transport	nhaK	✓	✓	✓				[37]
Mercury resistance	merA	✓	✓					[38]
	merR	✓	✓			✓		[39]
	merR1	✓	✓		✓		✓	[39]
Organic hydroperoxide tolerance	ohrB	✓	✓	✓	✓			[40]
Zinc tolerance	zntA	✓	✓	✓				[41]
Antibiotic Resistance
β-lactam resistance	ampC	✓	✓		✓			[42]
	bla			✓				[43]
Bicyclomycin resistance	bcr	✓	✓	✓	✓			[44]
Daunorubicin, doxorubicin resistance	drrA			✓	✓	✓	✓	[45]
	drrB				✓	✓	✓	[45–47]
Isoniazid resistance	iniA				✓			[48]
Fosmidomycin resistance	fsr	✓	✓	✓				[49]
Multidrug resistance	mmr					✓	✓	[50]
	stp			✓	✓	✓	✓	[51]
	sugE	✓	✓	✓	✓	✓	✓	[52, 53]