TABLE 2.

Overview of the physiological and morphological properties of BNST_ALG neurons in rat, mouse and macaque.

	Rat (Rattus norvegicus)				Mouse (Mus musculus)				Macaque (Macaca mulatta)
	Type I	Type II	Type III	Other	Type I	Type II	Type III	Other	Type I	Type II	Type III	Other
Incidence (%)	40–66% (Hammack et al., 2007; Rodríguez-Sierra et al., 2013; Daniel et al., 2017)	11–30% (Hammack et al., 2007; Rodríguez-Sierra et al., 2013; Daniel et al., 2017)	16–30% (Hammack et al., 2007; Rodríguez-Sierra et al., 2013; Daniel et al., 2017)	4–8% (Rodríguez-Sierra et al., 2013)	13% (Daniel et al., 2017)	22% (Daniel et al., 2017)	54% (Daniel et al., 2017)	11% (Daniel et al., 2017)	3% (Daniel et al., 2017)	16% (Daniel et al., 2017)	56% (Daniel et al., 2017)	25% (Daniel et al., 2017)
Spiking/firing pattern	RF,DF (Hammack et al., 2007; Rodríguez-Sierra et al., 2013; Daniel et al., 2017)	LTB, RBF (Hammack et al., 2007; Rodríguez-Sierra et al., 2013; Daniel et al., 2017)	RF, DF, fIR (Hammack et al., 2007; Rodríguez-Sierra et al., 2013; Daniel et al., 2017)	LF (Rodríguez-Sierra et al., 2013) SA (Rodríguez-Sierra et al., 2013)	RF,DF (Daniel et al., 2017; Walter et al., 2018; Miura et al., 2023)	noRBF (Daniel et al., 2017) RBF (Walter et al., 2018; Miura et al., 2023)	RF, DF, fIR (Daniel et al., 2017; Walter et al., 2018; Miura et al., 2023)	fAHP (Daniel et al., 2017)	RF,DF (Daniel et al., 2017)	LTB, RBF (Daniel et al., 2017)	DF, fIR (Daniel et al., 2017)	fAHP (Daniel et al., 2017) SF (Daniel et al., 2017)
Neuro- transmitter	GABA (McDonald, 1983; Sun and Cassell, 1993; Hammack et al., 2007; Nguyen et al., 2016; Daniel et al., 2017)	GABA (McDonald, 1983; Sun and Cassell, 1993; Hammack et al., 2007; Nguyen et al., 2016; Daniel et al., 2017)	GABA (McDonald, 1983; Sun and Cassell, 1993; Hammack et al., 2007; Nguyen et al., 2016; Daniel et al., 2017)	GABA and GLUT? (McDonald, 1983; Sun and Cassell, 1993; Hammack et al., 2007; Nguyen et al., 2016; Daniel et al., 2017)	GABA (Daniel et al., 2017)	GABA (Daniel et al., 2017)	GABA (Daniel et al., 2017)	GABA and GLUT? (Daniel et al., 2017)	GABA (Daniel et al., 2017)	GABA (Daniel et al., 2017)	GABA (Daniel et al., 2017)	GABA and GLUT? (Daniel et al., 2017)
Ion channel expression	Ih: HCN2 and HCN3 (Hammack et al., 2007; Hazra et al., 2011; Rodríguez-Sierra et al., 2013; Daniel et al., 2017) IA (Hammack et al., 2007; Hazra et al., 2011; Rodríguez-Sierra et al., 2013; Daniel et al., 2017)	Ih,: HCN1-HCN4 (Hammack et al., 2007; Hazra et al., 2011; Rodríguez-Sierra et al., 2013; Daniel et al., 2017) IT: CaV3.1-3.3 (Hammack et al., 2007; Hazra et al., 2011; Rodríguez-Sierra et al., 2013; Daniel et al., 2017)	IK(IR): Kir2.1-Kir2.4 (Hammack et al., 2007; Hazra et al., 2011; Rodríguez-Sierra et al., 2013; Daniel et al., 2017) IA (Hammack et al., 2007; Hazra et al., 2011; Rodríguez-Sierra et al., 2013; Daniel et al., 2017)	ID (Rodríguez-Sierra et al., 2013)	Ih (Daniel et al., 2017) IA (Hammack et al., 2007; Hazra et al., 2011; Rodríguez-Sierra et al., 2013; Daniel et al., 2017)	Ih (Daniel et al., 2017) IT (Daniel et al., 2017)	IK(IR) (Daniel et al., 2017) IA (Daniel et al., 2017)	?	Ih (Daniel et al., 2017)	Ih (Daniel et al., 2017) IT (Daniel et al., 2017)	IK(IR) (Daniel et al., 2017)	?
Neuropeptide markers		Enk, PKCδ (Daniel and Rainnie, 2016) NPY, SOM (McDonald and Zaric, 2015)	CRF (Dabrowska et al., 2013)	?	NPY (Walter et al., 2018)	Enk, PKCδ (Daniel and Rainnie, 2016) NPY (Walter et al., 2018)	CRF (Martin et al., 2010) NPY (Walter et al., 2018)	?	?	?	?	?
Morphology	Medium-spiny-like, round, polygonal, fusiform (McDonald, 1983; Larriva-Sahd, 2006)				Medium-spiny-like (Daniel et al., 2017)				Medium-spiny-like (Fudge and Haber, 2001) Long dendrites, large arborization (Daniel et al., 2017)

RF, regular firing; DF, delayed firing; LTB, low-threshold bursting; RBF, rebound firing; fIR, fast-inward rectification; LF, late firing; SA, spontaneous activity; fAhP, fast afterhyperpolarization; SF, stutter-firing; GABA, gamma-aminobutyric acid; GLUT, glutamate; CRF, corticotropin releasing factor; ENK, enkephalin; NPY, neuropeptide Y; PKCδ, protein kinase C type delta.