Figure 1.

Occurrence of biofilms in the human body. Biofilms have been found in numerous organs and tissues, including the middle ear and upper respiratory tract, oral cavity, cardiovascular system, lung, stomach, colon, urogenital system, bone, and soft tissue wounds. In the oral cavity, colon, and female reproductive tract, biofilms occur with varying frequencies in clinically healthy patients as well as those with infections or underlying conditions, while in other tissues biofilms are generally associated with infections. Figure created with BioRender.com.