Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Aug 30;10:1187490. doi: 10.3389/fcvm.2023.1187490

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2023 Nguyen, Imanishi, Li, Chau, Banerjee, Velatooru, Ko, Samanthapudi, Lee, Abe, McBeath, Deswal, Lin, Palaskas, Dantzer, Fujiwara, Borchrdt, Turcios, Olmsted-Davis, Kotla, Cooke, Wang, Abe and Le.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Increased lipid-laden lesions and fibrotic caps in SENP2 S344A KI mice: SENP2 S344A KI and WT mice were injected with a single dose of rAAV8-mPCSK9 and fed a high fat diet (HFD) for 16 weeks (42). (A) En face Oil Red O staining was performed to quantify lipid abundance and distribution. (C) The bone marrow transplantation (BMT) procedure was conducted (58). (D) Representative PCR data demonstrate the success of the BMT. (E) En face Oil Red O staining was performed on the BMT-generated models. (G) Aortic valve leaflet sections were stained with Masson's trichrome to evaluate changes in the aortic valves. (B, F, H–K) The graphs present quantified data from samples (n = 7–10) (*p < 0.05, **p < 0.01, unpaired t-test). N.S. indicates non-significant.