Table 1. Sensitivity analyses using weighted median, MR-Egger, and MVMR methods.
| Outcomes | Weighted median | MR-Egger | MVMR | |||
|---|---|---|---|---|---|---|
| OR (95% CI) | P | OR (95% CI) | P | OR (95% CI) | P | |
| VTE→ CHD | 1.03 (0.98-1.08) | 0.21 | 1.01 (0.92-1.11) | 0.83 | 1.05 (1.00-1.10) | 0.03 |
| DVT→ CHD | 1.02 (0.98-1.05) | 0.36 | 1.02 (0.94-1.09) | 0.69 | 1.03 (1.00-1.07) | 0.07 |
| PE→ CHD | 1.03 (0.98-1.08) | 0.23 | 0.89 (0.75-1.06) | 0.27 | 1.02 (0.98-1.05) | 0.38 |
| CHD→ VTE | 0.97 (0.86-1.08) | 0.57 | 0.89 (0.54-1.45) | 0.63 | 0.98 (0.91-1.06) | 0.64 |
| CHD→ DVT | 1.02 (0.88-1.18) | 0.81 | 0.78 (0.44-1.40) | 0.41 | 0.94 (0.85-1.06) | 0.32 |
| CHD→ PE | 1.02 (0.88-1.17) | 0.83 | 0.92 (0.59-1.43) | 0.72 | 1.00 (0.89-1.11) | 0.93 |
CHD: coronary heart disease; CI: confidence interval; DVT: deep venous thrombosis; MR: Mendelian randomization; MVMR: multivariable Mendelian randomization; OR: odd ratio; PE: pulmonary embolism; VTE: venous thromboembolism