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. 2023 Aug 30;14:1116392. doi: 10.3389/fimmu.2023.1116392

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Copyright © 2023 Ner-Gaon, Peleg, Gazit, Reiner-Benaim and Shay

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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EIF4H is differentially spliced in sepsis. (A) Skipped exon in EIF4H. The Sashimi plots of neutrophils (NEU; healthy and sepsis, top) and monocytes (MO; healthy and sepsis, bottom) display the number of mapped reads; the splice junctions are shown as arcs. Samples from healthy or sepsis are overlaid on one another. The numbers on each arc are the junction spanning read (JSR) counts of each sample. The order of the samples is the same for all junctions. (B) Bar plots of EIF4H skipped exon differentially spliced LeafCutter cluster (DS-LC) from neutrophils (NEU; fraction and counts of JSR in all samples, top) and monocytes (MO; fraction and counts of JSR in all samples, bottom) from all samples. The JSRs of each junction are colored in the colors of the arcs of that junction in (A).