Fig. 4.

Therapeutic effect of GENs in DSS-induced colitis. (A) (B) Measurement of colon length. (C) Colon thickness imaged by CT scan. (D) The weight loss of DSS-induced colitis mice treated with 1X PBS and GENs. (E) The Disease Activity Index (DAI) assessment. DAI index was evaluated with the three parameters (body weight loss, stool consistency, rectal bleeding). (F) Survival rate of Balb/C mice gavaged with 2.5% DSS treated with PBS and GENs. (G) Gene expression of inflammatory genes was analyzed. (H) Representative H&E stained colonic tissue from Balb/C mice with or without 2.5% DSS gavage at day 8 after treatment of GENs. (I) Evaluation of serum AST and ALT levels after administration of GENs (∗P < 0.05).