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. 2023 Aug 30;621(7978):381–388. doi: 10.1038/s41586-023-06459-w

Extended Data Fig. 4. Non-dorsolateral hippocampal spectral content during food anticipation.

Extended Data Fig. 4

(A) Z-score normalized difference spectrograms (sweet-fat – taste-neutral item) in the non-dorsolateral hippocampus (non-dlHPC) before (left spectrogram) and after (right spectrogram) correction for multiple comparisons. Colour bar indicates mean z-score power difference (using pooled channels as observations) between the two conditions compared to a null distribution. Outlined clusters (left spectrogram) reflect significant contiguous time-frequency voxels (p < 0.05, two-sided cluster-based permutation testing, 1000 permutations) before correction for multiple comparisons. Thresholded map displays significant time-frequency cluster (~ 7–12 Hz) after correction for multiple comparisons using cluster size (see methods). Note the absence of a cluster centred in ~4–6 Hz in the thresholded map. (B) 7–12 Hz mean z-score power time traces in the dlHPC (left traces) and non-dlHPC (right traces) hippocampal sites, respectively. 0-time indicates cue presentation. Note that while 7–12 Hz power is recruited in both subregions, condition specificity to water at this frequency range is only observed in non-dlHPC.