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. 2023 May 2;621(7978):396–403. doi: 10.1038/s41586-023-06127-z

Extended Data Fig. 3. Examples of the DFA representations for extended codons, modified nucleotides, and coding constraints.

Extended Data Fig. 3

a, Alternative genetic codes of serine, tryptophan, and threonine. b, Avoiding certain codon. On the left it shows the original DFA of serine (up), in which the red dashed arrows indicating UCA and UCG are chosen to be avoided, resulting in a new DFA (down). On the right it shows removing the rare amber STOP codon (UAG). c, Avoiding a specific adjacent codon pair. d, Extended serine DFA can include chemically modified nucleotides pseudouridine (Ψ), 6-Methyladenosine (m6A) and 5-methylcytosine (m5C).