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Schematic diagram of the spatial omics approach. (A) Laser capture microdissection (LCM)-based spatial imaging, (B) in situ hybridization (ISH)-based RNA imaging, (C) mass spectrometry imaging (MSI)-based spatial metabolomics, and (D) spatial barcode sequencing. NGS: next-generation sequencing; LC-MS: liquid chromatography-mass spectrometry; mRNA: messenger RNA.
