Fig. 1.

Lack of kinin B2 but not B1 receptors increases damage of injured muscle. A Representative photos from H&E staining of Tibial anterior (TA) muscles for all animal groups at indicated days after injury showing an inflammatory area (*), fibers centrally nucleated (arrow) and necrotic cells (arrowhead) and B and C injured area delimited (*). (Scale bars = 100 μm). (n = 5, all groups). D TA injury area normalized to cross-sectional area (square micrometer per square micrometer). Data are represented as mean ± SD. *P < 0.05 KO groups vs WT control group. #P < 0.05 B1KO vs other KOs. E Number of inflammatory cells within the areas of injury. High-power fields (HPF). Data are represented as mean ± SD. *P < 0.05 KO groups vs WT control group. #P < 0.05 B1KO vs others KOs. F Percentage of centronucleated cells within the areas of injury. High-power fields (HPF). Data are represented as mean ± SD. *P < 0.05 KO groups vs WT control group. # P < 0.05 all KO groups vs KO groups