Fig. 4.

Panel a reports the evolution over time of the median (95% CI) diastolic blood pressure (DBP) after 601 intakes of oral nimodipine in 49 patients. b Median DBP over time after PO nimodipine intake in the subgroups of intakes with (n = 62, 10%) and without a significant > 10% DBP drop. At time 0, data were available from 601 (100%) episodes. After 60 min, 120 min, 180 min, and 240 min, data were available from 590 (98%), 579 (96%), 435 (72%), and 268 (45%) intakes, respectively (and therefore not overlapping with the next dose of oral nimodipine intake). The 0 refers to the start of continuous nimodipine application. Values and bars are median values over 5 min, reported every 5 min. CI, confidence interval, PO, per os