Table 1:

Age-standardised incidence of major cancers in people living with HIV in Australia between 1982 – 2012 (per 100,000 person-years) in three age groups, and overall.

Cancer1	Age Group	1982-1995	1996-1999	2000-2004	2005-2008	2009-2012	p-value*
AID defining cancers
Kaposi sarcoma	Overall	996.70	305.20	123.85	63.04	64.79	<0.001
	15-34	791.77	295.36	98.84	36.59	48.73	<0.001
	35-64	1220.95	323.92	109.62	86.93	71.16	<0.001
	65-	144.70	0.00	35.54	0.00	19.87	0.995
Non-Hodgkin lymphoma	Overall	658.62	343.04	121.68	112.89	71.08	<0.001
	15-34	292.37	346.37	73.87	117.16	45.89	0.027
	35-64	770.93	362.86	152.35	101.65	91.62	<0.001
	65-	901.74	133.84	52.38	101.92	82.29	0.001
Infection related non-AID defining cancers
Anal cancer	Overall	26.82	18.76	25.40	38.41	44.97	0.002
	15-34	4.41	12.40	0.00	4.55	4.34	0.621
	35-64	24.49	16.99	41.13	41.69	66.44	<0.001
	65-	84.83	0.00	34.86	105.22	71.43	0.553
Hodgkin lymphoma	Overall	13.63	26.58	16.14	29.23	23.39	0.314
	15-34	10.48	18.20	5.90	9.11	4.35	0.222
	35-64	14.19	20.40	17.70	32.04	37.25	<0.001
	65-	0.00	45.27	34.62	41.38	24.14	0.550
Liver cancer	Overall	2.00	4.04	9.06	8.96	14.79	<0.001
	15-34	0.00	0.00	0.00	0.00	0.00	N/A
	35-64	4.13	8.35	13.32	18.53	26.65	<0.001
	65-	0.00	0.00	16.57	0.00	12.03	0.470
Head and neck cancer	Overall	10.67	2.87	9.61	5.77	7.64	0.765
	15-34	0.00	2.99	0.00	0.00	0.00	N/A
	35-64	22.05	3.72	14.43	11.93	15.79	0.839
	65-	0.00	0.00	16.67	0.00	0.00	N/A
Non-infection related non-AID defining cancers
Lip cancer	Overall	12.10	18.23	7.10	3.86	7.56	0.147
	15-34	1.88	0.00	0.00	4.55	0.00	0.917
	35-64	22.07	22.86	14.68	4.60	9.58	0.006
	65-	0.00	45.42	0.00	0.00	18.55	0.912
Lung cancer	Overall	13.85	26.48	27.47	16.72	31.17	0.300
	15-34	4.41	0.00	0.00	0.00	0.00	N/A
	35-64	9.88	39.82	29.04	27.09	39.96	0.227
	65-	47.42	45.71	85.02	22.89	75.01	0.716
Colorectal cancer	Overall	11.51	8.98	5.99	7.73	22.63	0.238
	15-34	0.00	0.00	0.00	0.00	7.47	N/A
	35-64	8.27	3.72	12.38	12.22	19.97	0.003
	65-	47.58	45.49	0.00	11.50	44.59	0525
Stomach cancer	Overall	7.44	0.00	7.47	8.34	5.81	0.665
	15-34	0.00	0.00	0.00	0.00	0.00	N/A
	35-64	0.00	0.00	10.03	0.00	9.91	0.382
	65-	47.10	0.00	16.58	52.81	6.45	0.736
Melanoma	Overall	39.61	31.98	28.02	30.67	33.00	0.249
	15-34	14.59	15.40	23.43	0.00	4.35	0.291
	35-64	57.25	42.09	21.48	32.09	37.33	0.142
	65-	47.42	0.00	16.72	95.97	84.77	0.132
Prostate cancer	Overall	49.72	35.47	24.28	66.39	39.44	0.853
	15-34	0.00	0.00	0.00	0.00	0.00	N/A
	35-64	59.00	16.43	5.48	44.66	50.17	0.869
	65-	134.18	174.35	137.00	283.65	96.13	0.906

^*Linear regression model p value for trend

¹ICD10/O-3 codes: Kaposi sarcoma 9140, 8000 if KS on AIDS Registry, non-Hodgkin lymphoma 9591 9596, 9670-9729, 9820-9837, 9940, 9948 and 9590 if ICD10 C82-C85; Diffuse large B cell lymphoma 9680, 9684, 9678, 9679; Burkitt 9687, 9826; CNS lymphoma, non-Hodgkin lymphoma with C70-C72 topography; Hodgkin lymphoma 9650-9667; anus C21; Head and Neck cancer C01-C10, excluding C07-C08; liver C22; lip C00; melanoma c43; trachea, bronchus and lung C33-C34; colorectal C18-C20; prostate C61