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. 2023 Aug 10;17(9):851–864. doi: 10.1111/crj.13670

TABLE 6.

The dose adjustment rate of inhaled drugs containing glucocorticoid of clinical phenotypes.

Dose adjustment rate (n,%) Neutrophilic Eosinophilic Mixed granulocytic
Doxophylline group Non‐doxophylline group Doxophylline group Non‐doxophylline group Doxophylline group Non‐doxophylline group
1st month Reduced 0 (0.0%) 0 (0.0%) 1 (4.8%) 0 (0.0%) 0 (0.0%) 0 (0.0%)
Increased 2 (3.3%) 3 (5.0%) 0 (0.0%) 0 (0.0%) 2 (4.5%) 3 (6.8%)
P Value 0.990 0.476 0.990
3rd months Reduced 10 (16.7%) 7 (11.7%) 1 (4.8%) 8 (38.1%) 5 (11.4%) 7 (15.9%)
Increased 2 (3.3%) 17 (28.3%) 4 (40.0%) 1 (9.1%) 7 (15.9%) 4 (9.1%)
P Value 0.003 0.016 0.170
6th months Reduced 13 (21.7%) 6 (10.0%) 7 (33.3%) 1 (4.8%) 5 (11.4%) 10 (22.7%)
Increased 3 (5.0%) 9 (15.0%) 0 (0.0%) 4 (19.0%) 3 (6.8%) 6 (13.6%)
P value 0.016 0.007 0.572